What is a common cause of acute cholecystitis?

Acute cholecystitis is primarily caused by the obstruction of the cystic duct, most commonly due to gallstones. When a gallstone lodges in the cystic duct, it prevents bile from flowing in and out of the gallbladder, leading to inflammation and infection. The buildup of bile can cause the gallbladder to become distended, leading to increased pressure and the potential for ischemia or necrosis if not treated promptly.

While pancreatitis can cause complications and is related to gallstones, it is not a direct cause of acute cholecystitis. Ulcers and liver failure do not have a direct connection to the mechanisms that lead to the inflammation of the gallbladder. The presence of gallstones is a significant risk factor for developing acute cholecystitis; therefore, it is recognized as the most common cause of this condition. Understanding the relationship between gallstones and the pathology of acute cholecystitis is essential for effective diagnosis and management.